Volume 8, Issue 4, July 2020, Page: 71-75
The Efficacy of Salinomycin Against Experimentally Infected Broiler Chickens with Field Isolates of Eimeria tenella in Khartoum State, Sudan
Mortada Mahgoub Osman Elhassan, College of Veterinary Medicine, University of Bahri, Khartoum, Sudan
Mona Abdelrahman Mohamed Khaier, College of Veterinary Medicine, University of Bahri, Khartoum, Sudan
Elgailani Ali Elamin, Faculty of Veterinary Medicine, University of Khartoum, Khartoum, Sudan
Received: Jun. 13, 2020;       Accepted: Jun. 28, 2020;       Published: Jul. 13, 2020
DOI: 10.11648/j.avs.20200804.11      View  66      Downloads  51
Abstract
Administration of feed-based anticoccidials, as preventive measure, is one of the great successes in disease control for the ever-expanding poultry industry. The present study aimed at evaluating the efficacy of salinomycin medication against experimental infection with Eimeria tenella isolated from a local farm in Khartoum, Sudan. Forty-five one-day-old male broiler chicks (Ross 308) were randomized into 3 equal sets (control, infected, and medicated treatment groups). Infection was established by inoculating each of 36 birds with 1×105 sporulated oocysts when they were 24 days old. After 6 days, 9 birds of each group were bled for sera and sacrificed for post mortem examination. Birds of infected non-medicated group developed caecal lesions typical of E. tenella infection. Birds of salinomycin treatment at the concentration of 60 gm/ton of feed had highly diminished lesion scores (0.33) compared to infected non-medicated bird (3.00). Packed cell volume (PCV), triglycerides and cholesterol in birds medicated with salinomycin did not show marked difference as compared to broilers in negative control. There was no significant difference (P>0.05) in the levels of total protein and the concentration of calcium and phosphorus amongst experimental groups. It is concluded that salinomycin averted the negative impact of coccidiosis caused by E. tenella on broiler chicks; indicating that it could be recommended for establishing an efficient coccidian control programs under Sudan conditions.
Keywords
Broilers, Efficacy, Eimeria tenella, Salinomycin, Sudan
To cite this article
Mortada Mahgoub Osman Elhassan, Mona Abdelrahman Mohamed Khaier, Elgailani Ali Elamin, The Efficacy of Salinomycin Against Experimentally Infected Broiler Chickens with Field Isolates of Eimeria tenella in Khartoum State, Sudan, Animal and Veterinary Sciences. Vol. 8, No. 4, 2020, pp. 71-75. doi: 10.11648/j.avs.20200804.11
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Reference
[1]
Fesseha H (2019). Probiotics and its potential role in poultry production: a review. Vet Med – Open J.; 4 (2): 69–76.
[2]
Firouzi S, Mosleh N, Tohidi Far SS, Taebipur MJ and Farjani Kish G (2014). Efficacy of anticoccidial vaccination of chickens via different routes: a comparative study. Bulg J Vet Med.; 17 (4): 293–301.
[3]
Noack S, Chapman HD and Selzer PM (2019). Anticoccidial drugs of the livestock industry. Parasitol Res.; 118 (7): 2009–2026.
[4]
Price KR (2012). Use of live vaccines for coccidiosis control in replacement layer pullets. J Appl Poult Res.; 21 (3): 679–692.
[5]
Williams RB (2005). Intercurrent coccidiosis and necrotic enteritis of chickens: Rational, integrated disease management by maintenance of gut integrity. Avian Pathol.; 34 (3): 159–180.
[6]
Blake DP, Clark EL, Macdonald SE, Thenmozhi V, Kundu K, Garg R. (2015). Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development. National Academy of Sciences. 112 (38): E5343–5350.
[7]
Shirley MW, Smith AL and Blake DP (2007). Challenges in the successful control of the avian coccidia. Vaccine; 25: 5540–5547.
[8]
Desouky A and Sultan K (2015). A preliminary survey on Eimeria species infecting chicken in Gharbia Governorate, Mid-Delta of Egypt. Egyptian Veterinary Medical Society of Parasitology Journa.; 11: 59–65.
[9]
Alzib AA and Abdelnabi GH (2017). Eimeria Spp. infection in some broiler farms in Khartoum State, Sudan. SOJ Vet Sci; 3 (4): 1-3.
[10]
Dalloul RA and Lillehoj HS (2006). Poultry coccidiosis: recent advancements in control measures and vaccine development. Expert Rev. Vaccines; 5 (1): 143–163.
[11]
Chapman HD and Jeffers TK (2015). Restoration of sensitivity to salinomycin in Eimeria following 5 flocks of broiler chickens reared in floor-pens using drug programs and vaccination to control coccidiosis. Poult Sci.; 94 (5): 943–946.
[12]
Quiroz-Castañeda RE and Dantán-González E (2015). Control of avian coccidiosis: Future and present natural alternatives. Biomed Res Int.; 11 pages, doi: 10.1155/2015/430610.
[13]
Chapman HD (2014). Milestones in avian coccidiosis research: a review. Am Hist Rev.; 119 (2): 501–511.
[14]
Shirley MW and Harvey DA (1996). Eimeria tenella: infection with a single sporocyst gives a clonal population. Parasitology; 112: 523–528.
[15]
NRC (1994). Nutrient Requirements of Poultry. Ninth Revi. Subcommittee on Poultry Nutrition, editor. Washington, DC: Natl. Acad. Press.
[16]
Johnson J, Reid WM (1970). Anticoccidial drugs: lesion scoring techniques in battery and floor-pen experiments with chickens. Exp Parasitol.; 28 (1): 30–36.
[17]
Peek HW and Landman WJM (2003). Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001. Avian Pathol.; 32 (4): 391–401.
[18]
Ojimelukwe AE, Emedhem DE, Agu GO, Nduka FO and Abah AE (2018). Populations of Eimeria tenella express resistance to commonly used anticoccidial drugs in southern Nigeria. Int J Vet Sci Med.; 0–1.
[19]
Ahmed A. Al-Gawad, Olfat A. Mahdy Aida AN El-Massry and Mohamed SA Al-Aziz (2012). Studies on coccidia of egyptian balady breed chickens. Life Sci J.; 9 (3).
[20]
Abu-Akkada SS and Awad AM (2012). Isolation, propagation, identification and comparative pathogenicity of five Egyptian field strains of Eimeria tenella from broiler chickens in five different provinces in Egypt. Res Vet Sci.; 92 (1): 92–95.
[21]
Bozkurt M, Aysul N, Küçükyilmaz K, Aypak S, Ege G, Çatli AU (2014). Efficacy of in-feed preparations of an anticoccidial, multienzyme, prebiotic, probiotic, and herbal essential oil mixture in healthy and Eimeria spp.-infected broilers. Poult Sci.; 93 (2): 389–399.
[22]
Mathis G, Schaeffer J, Cookson K, Dickson J, LaVorgna M and Waldrip D (2014). Effect of lasalocid or salinomycin administration on performance and immunity following coccidia vaccination of commercial broilers. J Appl Poult Res.; 23 (4): 577–585.
[23]
Conway DP, Sasai K, Gaafar SM and Smothers CD (1993). Effects of different levels of oocyst inocula of Eimeria acervulina, E. tenella, and E. maxima on plasma constituents, packed cell vo lume, lesion scores, and performance in chickens. Avian Dis.; 37 (1): 118.
[24]
Adamu M, Boonkaewwan C, Gongruttananun N and Vongpakorn M (2013). Hematological, biochemical and histopathological changes caused by coccidiosis in chickens. Kasetsart J - Nat Sci.; 47 (2): 238–246.
[25]
Hirani ND, Hasnani JJ, Pandya SS and Patel PV (2018). Haematological changes in broiler birds with induced caecal coccidiosis following prophylaxis with different coccidiostats. Int J Curr Microbiol Appl Sci.; 7 (04): 1094–1100.
[26]
Mondal DK, Chattopadhyay S, Batabyal S, Bera AK and Bhattacharya D (2011). Plasma biochemical indices at various stages of infection with a field isolate of Eimeria tenella in broiler chicken. Vet World.; 4 (9): 404–409.
[27]
Basith AS, Rajavelu G and Manohar MB (1998). Biochemical studies in experimental Eimeria necatrix infection in chickens. Indian Vet J.; 75 (10): 876–878.
[28]
Patra G. Rajkhowa, Ayub M, Tiwary JG and Sailo L (2009). Studies on clinical, gross, histopathological and biochemical parameters in broiler birds suffered from Eimeria necatrix infection in Aizawl District of Mizoram, India. Int J Poult Sci.; 8 (11): 1104–6.
[29]
Peek HW and Landman WJM (2011). Coccidiosis in poultry: anticoccidial products, vaccines and other prevention strategies. Vet Q.; 31 (3): 143–161.
[30]
Györke A, Kalmár Z, Pop LM and Şuteu OL (2016). The economic impact of infection with Eimeria spp. in broiler farms from Romania. Rev Bras Zootec.; 45 (5): 273–280.
[31]
Chapman HD Jeffers TK (2014). Vaccination of chickens against coccidiosis ameliorates drug resistance in commercial poultry production. International Journal for Parasitology: Drugs and Drug Resistance; 4 (3): 214–217.
Browse journals by subject