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Research Article |

Effects of Guanidinoacetic Acid (GAA) Supplementation on Zootechnical Performance and Biochemical Parameters of Broiler Chickens in Dakar Region, Senegal

Creatine, a natural component synthesized in liver and kidneys from guanidinoacetic acid (GAA), is mainly used in muscle tissue, due to its major role in energy metabolism. Approximately 50% of the daily requirement should be provided by the diet, yet this creatine is not stable as a feed additive under current tropical feed manufacturing conditions. This study was therefore undertaken from April to June 2021 in Dakar region, to assess the effects of GAA supplementation on growth performance and biochemical parameters of broilers in Senegal. It involved 550 unsexed day-old broiler chicks of Cobb500 strain with an average live weight (ALW) of 44.8 g. They were randomly divided into 2 batches of 275 birds each, subdivided into 5 replicates of 55 birds, corresponding respectively to two iso-nutritional dietary treatments, T-GAA0 (control diet) and S-GAA0.06 (control supplemented at 0.06% GAA). Raised according to recommended densities during the different rearing phases, the birds were ad libitum watered with tap drinking water and fed with these two diets presented in crumb (at start-up) and in pellet forms (during growth-finishing). Data collected or calculated, i.e. ALW, average daily gain (ADG), daily feed intake (DFI) and water consumption (DWC), feed conversion ratio (FCR), mortality rate (MR), carcass weight (CW), dressing carcass (DC), organ weights, blood total protein, albumin, creatinine, uric acid, alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT) levels per dietary treatment, were subjected to Student's t analysis using SPSS software at the 5% threshold to compare means. Results showed that supplementing diet with GAA (at 0.06%) had no adverse effect on broilers’ health and their growth performance. It significantly (p<0.05) increased ALW (1923 vs.1796 g), ADG (45 vs. 42 g/day), DFI (93 vs. 91 g/bird/day), DWC (286 vs. 275 mL/bird/day), CW (1623 vs. 1526 g) and heart and gizzard weights, while reduced FCR (2.13 vs. 2.46), DC (84.4 vs. 85%) and liver weight (56 vs. 61 g) in birds compared to controls. It was also accompanied by a significant increase in blood albumin (17.5 vs. 16.9 g/L), creatinine (114.3 vs. 112.9 µmol/L), uric acid (0.86 vs. 0.78 mmol/L) and ALAT (34.3 vs. 27.5 UI/L) levels in birds concerned compared with controls, whereas total protein and ASAT levels were similar (p˃0.05). Indeed, all biochemical parameters levels studied were in line with the corresponding reference values in broilers both for controls and supplemented birds, with the exception of uric acid content in blood which were higher.

Broilers, Guanidinoacetic Acid, Growth performance, Feeding, Biochemical Parameters, Senegal

APA Style

Ayssiwede, S. B., Kalandi, M., Atchiwassa, S., Kouadio, K. D., Kabore, B., et al. (2024). Effects of Guanidinoacetic Acid (GAA) Supplementation on Zootechnical Performance and Biochemical Parameters of Broiler Chickens in Dakar Region, Senegal. Animal and Veterinary Sciences, 12(1), 1-10. https://doi.org/10.11648/j.avs.20241201.11

ACS Style

Ayssiwede, S. B.; Kalandi, M.; Atchiwassa, S.; Kouadio, K. D.; Kabore, B., et al. Effects of Guanidinoacetic Acid (GAA) Supplementation on Zootechnical Performance and Biochemical Parameters of Broiler Chickens in Dakar Region, Senegal. Anim. Vet. Sci. 2024, 12(1), 1-10. doi: 10.11648/j.avs.20241201.11

AMA Style

Ayssiwede SB, Kalandi M, Atchiwassa S, Kouadio KD, Kabore B, et al. Effects of Guanidinoacetic Acid (GAA) Supplementation on Zootechnical Performance and Biochemical Parameters of Broiler Chickens in Dakar Region, Senegal. Anim Vet Sci. 2024;12(1):1-10. doi: 10.11648/j.avs.20241201.11

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